Online resources of cancer data: barriers, benefits and lessons

被引：14

作者：

Gadaleta, Emanuela ^{[1
]}

Lemoine, Nicholas R. ^{[1
]}

Chelala, Claude ^{[1
]}

机构：

[1] Barts & London Sch Med QMUL, Ctr Mol Oncol & Imaging, Inst Canc, London EC1M 6BQ, England

来源：

BRIEFINGS IN BIOINFORMATICS | 2011年 / 12卷 / 01期

关键词：

data-mining; heterogeneity and isolation of data; interoperability; online cancer resources; GENE-EXPRESSION OMNIBUS; MICROARRAY DATA; NCBI GEO; PLATFORM; BIOMART; CYBERINFRASTRUCTURE; ARRAYEXPRESS; INTEGRATION; SUBMISSION; DATABASES;

D O I：

10.1093/bib/bbq010

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

With advances in high-throughput techniques, the volume of data generated has resulted in the creation of a plethora of resources for the cancer research community. However, a key factor in the utility, sustainability and future use of a novel resource lies in its ability to allow for data sharing and to be interoperable with major international cancer research efforts. This article will introduce some of these efforts, the interoperable cancer data-mining resources and repositories, from a user-perspective. Some of the considerations to be addressed when building interoperable, sustainable cancer resources will be discussed with case studies-hoping this will prove useful for researchers designing their own cancer databases.

引用

页码：52 / 63

页数：12

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