An introduction to lymphocyte and viral dynamics: the power and limitations of mathematical analysis

被引：29

作者：

Asquith, B ^{[1
]}

Bangham, CRM ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Wright Fleming Inst, Dept Immunol, London W2 1PG, England

来源：

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 2003年 / 270卷 / 1525期

关键词：

mathematical model; lymphocyte dynamics; theoretical immunology;

D O I：

10.1098/rspb.2003.2386

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mathematics is a useful tool in the analysis and understanding of population dynamic aspects of the immune response. However, the power of mathematical modelling in immunology is frequently limited by the shortage of experimental data. Here, we review the contribution of mathematics to two areas of immunology. We highlight the problem caused by lack of knowledge of the system, which can greatly restrict the use of mathematics and lead to errors caused by model-specific results.

引用

页码：1651 / 1657

页数：7

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