Molecular epidemiology of orf513-bearing class 1 integrons in multiresistant clinical isolates from Argentinean hospitals

被引：39

作者：

Arduino, SM

Catalano, M

Orman, BE

Roy, PH

Centrón, D

机构：

[1] Univ Buenos Aires, Fac Med, Dept Microbiol, RA-1121 Buenos Aires, DF, Argentina

[2] Univ Laval, Fac Sci & Genie, Dept Biochim, St Foy, PQ G1K 7P4, Canada

[3] CHU Laval, Ctr Rech, Ctr Rech Infectiol, Quebec City, PQ G1V 4G2, Canada

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 12期

关键词：

D O I：

10.1128/AAC.47.12.3945-3949.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The spread of orf513-bearing class 1 integrons is associated with bla(CTX-M-2) in gram-negative clinical isolates in Argentina, with In35 being the most frequently found integron (74%). Among 65 isolates without bla(CTX-M-2), only one harbored a novel orf513-bearing class 1 integron with the dfrA3b gene. The finding of orf513 not associated with class 1 integrons in two gram-positive strains indicates the widespread occurrence of this putative site-specific recombinase.

引用

收藏

页码：3945 / 3949

页数：5

相关论文

共 21 条

[1] blaCTX-M-2 is located in an unusual class 1 integron (In35) which includes Orf513 [J].

Arduino, SM ;

Roy, PH ;

Jacoby, GA ;

Orman, BE ;

Pineiro, SA ;

Centron, D .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (07) :2303-2306

[2] ColE1-Like plasmid pIP843 of Klebsiella pneumoniae encoding extended-spectrum β-lactamase CTX-M-17 [J].

Cao, V ;

Lambert, T ;

Courvalin, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (05) :1212-1217

[3] Three cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People's Republic of China [J].

Chanawong, A ;

M'Zali, FH ;

Heritage, J ;

Xiong, JH ;

Hawkey, PM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (03) :630-637

[4] Extended-spectrum β-lactamase-producing strain of Acinetobacter baumannii isolated from a patient in France [J].

Poirel, L ;

Karim, A ;

Mercat, A ;

Le Thomas, I ;

Vahaboglu, H ;

Richard, C ;

Nordmann, P .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1999, 43 (01) :157-158

[5] Novel class 1 integron (InS21) carrying blaCTX-M-2 in Salmonella enterica serovar infantis [J].

Di Conza, J ;

Ayala, JA ;

Power, P ;

Mollerach, M ;

Gutkind, G .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (07) :2257-2261

[6] THE STRUCTURE OF A PARTIAL DUPLICATION IN THE INTEGRON OF PLASMID PDGO100 [J].

HALL, RM ;

STOKES, HW .

PLASMID, 1990, 23 (01) :76-79

[7] Plasmid-mediated extended-spectrum β-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp1 [J].

Karim, A ;

Poirel, L ;

Nagarajan, S ;

Nordmann, P .

FEMS MICROBIOLOGY LETTERS, 2001, 201 (02) :237-241

[8] PCR MAPPING OF INTEGRONS REVEALS SEVERAL NOVEL COMBINATIONS OF RESISTANCE GENES [J].

LEVESQUE, C ;

PICHE, L ;

LAROSE, C ;

ROY, PH .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (01) :185-191

[9] Many class I integrons comprise distinct stable structures occurring in different species of Enterobacteriaceae isolated from widespread geographic regions in Europe [J].

Martinez-Freijo, P ;

Fluit, AC ;

Schmitz, FJ ;

Verhoef, J ;

Jones, ME .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (03) :686-689

[10] Novel gene cassettes and integrons [J].

Peters, EDJ ;

Leverstein-van Hall, MA ;

Box, ATA ;

Verhoef, J ;

Fluit, AC .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (10) :2961-2964