Bioluminescence imaging: progress and applications

被引：277

作者：

Badr, Christian E. ^{[1
,3
]}

Tannous, Bakhos A. ^{[1
,2
,3
]}

机构：

[1] Massachusetts Gen Hosp, Dept Neurol, Ctr Neurosci, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Ctr Mol Imaging Res, Boston, MA 02114 USA

[3] Harvard Univ, Sch Med, Program Neurosci, Boston, MA 02115 USA

来源：

TRENDS IN BIOTECHNOLOGY | 2011年 / 29卷 / 12期

关键词：

MESENCHYMAL STEM-CELLS; PROTEIN-PROTEIN INTERACTIONS; 2-STEP TRANSCRIPTIONAL AMPLIFICATION; REPORTER GENE-EXPRESSION; IN-VIVO; T-CELLS; FIREFLY LUCIFERASE; SECRETORY PATHWAY; MOUSE MODELS; SELF-RENEWAL;

D O I：

10.1016/j.tibtech.2011.06.010

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 090105 [作物生产系统与生态工程];

摘要：

Application of bioluminescence imaging has increased tremendously in the past decade and has significantly contributed to core conceptual advances in biomedical research. This technology provides valuable means for monitoring of different biological processes in immunology, oncology, virology and neuroscience. In this review, we discuss current trends in bioluminescence and its application in different fields with an emphasis on cancer research.

引用

页码：624 / 633

页数：10

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