Implementing an X-ray validation pipeline for the Protein Data Bank

被引：81

作者：

Gore, Swanand ^{[1
]}

Velankar, Sameer ^{[1
]}

Kleywegt, Gerard J. ^{[1
]}

机构：

[1] EMBL EBI, Prot Data Bank Europe PDBe, Cambridge CB10 1SD, England

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY | 2012年 / 68卷

基金：

英国惠康基金;

关键词：

REFINEMENT; ERRORS;

D O I：

10.1107/S0907444911050359

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

There is an increasing realisation that the quality of the biomacromolecular structures deposited in the Protein Data Bank (PDB) archive needs to be assessed critically using established and powerful validation methods. The Worldwide Protein Data Bank (wwPDB) organization has convened several Validation Task Forces (VTFs) to advise on the methods and standards that should be used to validate all of the entries already in the PDB as well as all structures that will be deposited in the future. The recommendations of the X-ray VTF are currently being implemented in a software pipeline. Here, ongoing work on this pipeline is briefly described as well as ways in which validation-related information could be presented to users of structural data.

引用

页码：478 / 483

页数：6

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