Additive manufacturing of hydroxyapatite bioceramic scaffolds: Dispersion, digital light processing, sintering, mechanical properties, and biocompatibility

被引:153
作者
Feng, Chengwei [1 ]
Zhang, Keqiang [1 ]
He, Rujie [1 ]
Ding, Guojiao [1 ]
Xia, Min [2 ]
Jin, Xinxin [3 ]
Xie, Chen [4 ]
机构
[1] Beijing Inst Technol, Inst Adv Struct Technol, Beijing 100081, Peoples R China
[2] Beijing Inst Technol, Sch Mat Sci & Engn, Beijing 100081, Peoples R China
[3] Harbin Univ Sci & Technol, Sch Mat Sci & Engn, Harbin 150040, Peoples R China
[4] Shanghai Aircraft Mfg Co Ltd, Shanghai 201324, Peoples R China
基金
中国国家自然科学基金;
关键词
additive manufacturing; digital light processing; vat photopolymerization; hydroxyapatite; bioceramic scaffold; 3D; STEREOLITHOGRAPHY; CERAMICS; COMPOSITE; CALCIUM; FABRICATION;
D O I
10.1007/s40145-020-0375-8
中图分类号
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号
081705 [工业催化]; 082905 [生物质能源与材料];
摘要
Hydroxyapatite (HA) bioceramic scaffolds were fabricated by using digital light processing (DLP) based additive manufacturing. Key issues on the HA bioceramic scaffolds, including dispersion, DLP fabrication, sintering, mechanical properties, and biocompatibility were discussed in detail. Firstly, the effects of dispersant dosage, solid loading, and sintering temperature were studied. The optimal dispersant dosage, solid loading, and sintering temperature were 2 wt%, 50 vol%, and 1250 degrees C, respectively. Then, the mechanical properties and biocompatibility of the HA bioceramic scaffolds were investigated. The DLP-prepared porous HA bioceramic scaffold was found to exhibit excellent mechanical properties and degradation behavior. From this study, DLP technique shows good potential for manufacturing HA bioceramic scaffolds.
引用
收藏
页码:360 / 373
页数:14
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