Synthesis of novel sialylmimetics as biological probes

被引：12

作者：

Bradley, SJ

Fazli, A

Kiefel, MJ

von Itzstein, M

机构：

[1] Griffith Univ, Ctr Biomol Sci & Drug Discovery, Gold Coast Mail Ctr, Qld 9726, Australia

[2] Monash Univ, Dept Med Chem, Parkville, Vic 3052, Australia

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 12期

关键词：

D O I：

10.1016/S0960-894X(01)00276-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Glycomimetics are increasingly being recognised as powerful tools in the search for novel compounds that possess useful biological properties. This paper describes our preliminary efforts towards the development of novel mimetics of sialic acid thioglycosides. These sialylmimetics are readily prepared and have been shown, in some instances, to have biological properties similar to sialic acid thioglycosides. (C) 2001 Elsevier Science Ltd. All rights reserved.

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收藏

页码：1587 / 1590

页数：4

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