Direct synthesis of hetero-biaryl compounds containing an unprotected NH2 group via Suzuki-Miyaura reaction

被引：103

作者：

Itoh, T ^{[1
]}

Mase, T ^{[1
]}

机构：

[1] Banyu Pharmaceut Co Ltd, Proc Res, Proc R&D, Okazaki, Aichi 4440858, Japan

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 20期

关键词：

Suzuki-Miyaura reaction; unprotected NH2 group; D-t-BPF;

D O I：

10.1016/j.tetlet.2005.03.053

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hetero-biaryl compounds were prepared via the Suzuki-Miyaura coupling reaction of hetero-aryl moieties containing an unprotected NH2 group and arylboronic acids. D-t-BPF was found to be an efficient ligand for the cross-coupling of NH2-unprotected hetero-aryl chlorides with phenylboronic acid. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：3573 / 3577

页数：5

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