Simple, high yielding synthesis of trifunctional fluorescent lanthanide chelates

被引：19

作者：

Griffin, JMM ^{[1
]}

Skwierawska, AM ^{[1
]}

Manning, HC ^{[1
]}

Marx, JN ^{[1
]}

Bornhop, DJ ^{[1
]}

机构：

[1] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 23期

关键词：

1,4,7,10-tetraazacyclododecane; lanthanide; fluorescence; conjugates; chelate;

D O I：

10.1016/S0040-4039(01)00620-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In an effort to produce strong fluorophores which are conjugated to biologically active substrates, we report a facile, high yielding synthesis of conjugable lanthanide chelates based on the cyclen (1,4,7,10-tetraazacyclododecane) macrocycle. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：3823 / 3825

页数：3

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