Progress and prospects: Gene therapy clinical trials (part 2)

被引：58

作者：

Alton, Eric ^{[1
]}

Ferrari, Stefano ^{[1
]}

Griesenbach, Uta ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Gene Therapy, NHLI, London, England

来源：

GENE THERAPY | 2007年 / 14卷 / 22期

关键词：

clinical trials; skin diseases; Huntington's disease; Alzheimer's disease; HIV/; AIDS; OCT; hemophilia; ADA-SCID; cancer; CILIARY NEUROTROPHIC FACTOR; LONG-TERM CORRECTION; PHASE-I TRIAL; HUNTINGTONS-DISEASE; T-LYMPHOCYTES; HEMOPHILIA; EXPRESSION; CANCER; ADA; SURVIVAL;

D O I：

10.1038/sj.gt.3303033

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This is the second part of a review summarizing progress and prospects in gene therapy clinical research. Twenty key diseases/strategies are succinctly described and commented on by leaders in the field. This part includes clinical trials for skin diseases, neurological disorders, HIV/AIDS, ornithine transcarbamylase deficiency, alpha(1)-antitrypsin deficiency, haemophilia and cancer.

引用

页码：1555 / 1563

页数：9

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