Stereoselective Michael addition of trimethyl aluminium to nitro acrylates: a route to 2-methyl-3-amino propionic acid

被引：44

作者：

Eilitz, U ^{[1
]}

Lessmann, F ^{[1
]}

Seidelmann, O ^{[1
]}

Wendisch, V ^{[1
]}

机构：

[1] ChiroBlock Ltd, D-06766 Wolfen, Germany

来源：

TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 20期

关键词：

D O I：

10.1016/S0957-4166(03)00575-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The copper(I)-catalysed Michael addition of trimethyl aluminium to nitro acrylates yields 2-methyl-3-nitro propionic acid esters on a 200 g scale with enantiomeric excesses up to 92%. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：3095 / 3097

页数：3

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