Asymmetric conjugate addition of diethyl zinc to enones with tartrate chiral phosphite ligands

被引：87

作者：

Alexakis, A

Vastra, J

Burton, J

Mangeney, P

机构：

[1] Lab. de Chim. des Organo-Elements, URA 473 CNRS, Univ. Pierre et Marie Curie, 75252 Paris Cedex 05, 4, Place Jussieu

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 19期

关键词：

D O I：

10.1016/S0957-4166(97)00409-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The asymmetric conjugate addition of diethyl zinc to cyclohexen-2-one occurs with 0.5% copper (II) triflate and 1% chiral phosphite. Cyclic phosphites derived from various tartrates gave a moderate enantiomeric excess. The nature of the exocyclic substituent of the dioxaphospholane ring is important, but the chiral induction is imposed by the tartrate framework. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：3193 / 3196

页数：4

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