A formal synthesis of the syributins and secosyrins and a synthetic approach towards the syringolides

被引：20

作者：

Carda, M ^{[1
]}

Castillo, E

Rodríguez, S

Falomir, E

Marco, JA

机构：

[1] Univ Jaume 1, Dept Quim Inorgan & Organ, E-12080 Castellon, Spain

[2] Univ Valencia, Dept Quim Organ, E-46100 Valencia, Spain

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(98)01944-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The indium-mediated allylation of a protected derivative of D-xylulose in aqueous THF is highly diastereoselective. The obtained product has been converted in four steps into a spiro lactone previously transformed into syributins and secosyrins. This remarkably short reaction sequence constitutes therefore a formal synthesis of these compounds and provides also a promising synthetic approach towards the syringolides. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：8895 / 8896

页数：2

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