One-carbon homologation of carboxylic acids via BtCH2TMS:: A safe alternative to the Arndt-Eistert reaction

被引：22

作者：

Katritzky, AR ^{[1
]}

Zhang, SM

Hussein, AHM

Fang, YF

Steel, PJ

机构：

[1] Univ Florida, Dept Chem, Ctr Heterocycl Cpds, Gainesville, FL 32611 USA

[2] Univ Canterbury, Dept Chem, Christchurch 1, New Zealand

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 16期

关键词：

D O I：

10.1021/jo0017640

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Carboxylic acids are converted into the corresponding homologated acids or esters, using easily available 1-(trimethylsilylmethyl)benzotriazole (1) as a one-carbon synthon. The effectiveness of the reaction has been investigated on six aryl and seven alkyl carboxylic acids.

引用

页码：5606 / 5612

页数：7

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