Adverse Events in Cancer Genetic Testing Medical, Ethical, Legal, and Financial Implications

被引:77
作者
Brierley, Karina L. [1 ]
Blouch, Erica [2 ]
Cogswell, Whitney [3 ]
Homer, Jeanne P. [4 ]
Pencarinha, Debbie [5 ]
Stanislaw, Christine L. [6 ]
Matloff, Ellen T. [1 ]
机构
[1] Yale Univ, Sch Med, Yale Canc Ctr, New Haven, CT 06510 USA
[2] Massachusetts Gen Hosp, Ctr Canc Risk Assessment, Boston, MA 02114 USA
[3] Med Ctr Cent Georgia, Macon, GA USA
[4] Hoag Hosp, Newport Beach, CA USA
[5] Wellmont Canc Inst, Kingsport, TN USA
[6] Emory Univ, Dept Human Genet, Atlanta, GA 30322 USA
关键词
genetic counseling; genetic testing; BRCA1; BRCA2; Lynch syndrome; cancer genetics; NONPOLYPOSIS COLORECTAL-CANCER; PRIMARY-CARE PHYSICIANS; KNOWLEDGE; HEALTH; US; RECOMMENDATIONS; AWARENESS; BARRIERS; BREAST;
D O I
10.1097/PPO.0b013e3182609490
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cancer genetic counseling and testing are now integral services in progressive cancer care. There has been much debate over whether these services should be delivered by providers with specialized training in genetics or by all clinicians. Adverse outcomes resulting from cancer genetic counseling and testing performed by clinicians without specialization in genetics have been reported, but formal documentation is sparse. In this review, we present a series of national cases illustrating major patterns of errors in cancer genetic counseling and testing and the resulting impact on medical liability, health care costs, and the patients and their families.
引用
收藏
页码:303 / 309
页数:7
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