Candida prosthetic valve endocarditis cured by caspofungin therapy without valve replacement

被引：32

作者：

Rajendram, R ^{[1
]}

Alp, NJ

Mitchell, AR

Bowler, ICJW

Forfar, JC

机构：

[1] John Radcliffe Hosp, Dept Cardiol, Oxford OX3 9DU, England

[2] John Radcliffe Hosp, Dept Microbiol, Oxford OX3 9DU, England

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 40卷 / 09期

关键词：

D O I：

10.1086/429322

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A 64-year-old woman with a mechanical mitral valve prosthesis developed late-onset Candida endocarditis. Blood cultures grew Candida glabrata and Candida krusei. Transesophageal echocardiography demonstrated vegetations on the valve. The patient was not medically fit for valve replacement, but her condition was successfully treated with 6 weeks of intravenous caspofungin therapy.

引用

页码：E72 / E74

页数：3

共 17 条

[1] In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872) [J].

Bartizal, K ;

Gill, CJ ;

Abruzzo, GK ;

Flattery, AM ;

Kong, L ;

Scott, PM ;

Smith, JG ;

Leighton, CE ;

Bouffard, A ;

Dropinski, JF ;

Balkovec, J .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (11) :2326-2332

[2] NEW CRITERIA FOR DIAGNOSIS OF INFECTIVE ENDOCARDITIS - UTILIZATION OF SPECIFIC ECHOCARDIOGRAPHIC FINDINGS [J].

DURACK, DT ;

LUKES, AS ;

BRIGHT, DK ;

ALBERTS, MJ ;

BASHORE, TM ;

COREY, GR ;

DOUGLAS, JM ;

GRAY, L ;

HARRELL, FE ;

HARRISON, JK ;

HEINLE, SA ;

MORRIS, A ;

KISSLO, JA ;

NICELY, LM ;

OLDHAM, N ;

PENNING, LM ;

SEXTON, DJ ;

TOWNS, M ;

WAUGH, RA .

AMERICAN JOURNAL OF MEDICINE, 1994, 96 (03) :200-209

[3] Fungal endocarditis: Evidence in the world literature, 1965-1995 [J].

Ellis, ME ;

Al-Abdely, H ;

Sandridge, A ;

Greer, W ;

Ventura, W .

CLINICAL INFECTIOUS DISEASES, 2001, 32 (01) :50-62

[4] In vitro pharmacodynamic properties of MK-0991 determined by time-kill methods [J].

Ernst, EJ ;

Klepser, ME ;

Ernst, ME ;

Messer, SA ;

Pfaller, MA .

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 1999, 33 (02) :75-80

[5] HOSPITAL-ACQUIRED INFECTIOUS ENDOCARDITIS NOT ASSOCIATED WITH CARDIAC-SURGERY - AN EMERGING PROBLEM [J].

FERNANDEZGUERRERO, ML ;

VERDEJO, C ;

AZOFRA, J ;

DEGORGOLAS, M .

CLINICAL INFECTIOUS DISEASES, 1995, 20 (01) :16-23

[6] In vitro activities of semisynthetic pneumocandin L-733,560 against fluconazole-resistant and -susceptible Candida albicans isolates [J].

MartinezSuarez, JV ;

RodriguezTudela, JL .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (05) :1277-1279

[7] Comparison of caspofungin and amphotericin B for invasive candidiasis. [J].

Mora-Duarte, J ;

Betts, R ;

Rotstein, C ;

Colombo, AL ;

Thompson-Moya, L ;

Smietana, J ;

Lupinacci, R ;

Sable, C ;

Kartsonis, N ;

Perfect, J .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (25) :2020-2029

[8]

Nelson PW, 1997, J MED VET MYCOL, V35, P285

[9] Variation in susceptibility of bloodstream isolates of candida glabrata to fluconazole according to patient age and geographic location [J].

Pfaller, MA ;

Messer, SA ;

Boyken, L ;

Tendolkar, S ;

Hollis, RJ ;

Diekema, DJ .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (05) :2176-2179

[10] Role of sentinel surveillance of candidemia: Trends in species distribution and antifungal susceptibility [J].

Pfaller, MA ;

Diekema, DJ .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (10) :3551-3557

← 1 2 →