The age of crosstalk: Phosphorylation, ubiquitination, and beyond

被引:719
作者
Hunter, Tony [1 ]
机构
[1] Salk Inst Biol Studies, La Jolla, CA 92037 USA
关键词
D O I
10.1016/j.molcel.2007.11.019
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Crosstalk between different types of posttranslational modification is an emerging theme in eukaryotic biology. Particularly prominent are the multiple connections between phosphorylation and ubiquitination, which act either positively or negatively in both directions to regulate these processes.
引用
收藏
页码:730 / 738
页数:9
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共 42 条
[1]   A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression [J].
Besson, A ;
Gurian-West, M ;
Chen, XY ;
Kelly-Spratt, KS ;
Kemp, CJ ;
Roberts, JM .
GENES & DEVELOPMENT, 2006, 20 (01) :47-64
[2]   Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event [J].
Bhandari, Rashna ;
Saiardi, Adolfo ;
Ahmadibeni, Yousef ;
Snowman, Adele M. ;
Resnick, Adam C. ;
Kristiansen, Troels Z. ;
Molina, Henrik ;
Pandey, Akhilesh ;
Werner, J. Kent, Jr. ;
Juluri, Krishna R. ;
Xu, Yong ;
Prestwich, Glenn D. ;
Parang, Keykavous ;
Snyder, Solomon H. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (39) :15305-15310
[3]   Covalent modifications of histones during development and disease pathogenesis [J].
Bhaumik, Sukesh R. ;
Smith, Edwin ;
Shilatifard, Ali .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2007, 14 (11) :1008-1016
[4]   The SCF ubiquitin ligase: Insights into a molecular machine [J].
Cardozo, T ;
Pagano, M .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2004, 5 (09) :739-751
[5]   Ubiquitin signalling in the NF-κB pathway [J].
Chen, ZJJ .
NATURE CELL BIOLOGY, 2005, 7 (08) :758-U19
[6]   SUMO-Specific protease 1 is essential for stabilization of HIF1α during hypoxia [J].
Cheng, Jinke ;
Kang, Xunlei ;
Zhang, Sui ;
Yeh, Edward T. H. .
CELL, 2007, 131 (03) :584-595
[7]   Hsp90 recognizes a common surface on client kinases [J].
Citri, Ami ;
Harari, Daniel ;
Shohat, Galit ;
Ramakrishnan, Parameswaran ;
Gan, Judith ;
Lavi, Sara ;
Eisenstein, Miriam ;
Kimchi, Adi ;
Wallach, David ;
Pietrokovski, Shmuel ;
Yarden, Yosef .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (20) :14361-14369
[8]   Binary switches and modification cassettes in histone biology and beyond [J].
Fischle, W ;
Wang, YM ;
Allis, CD .
NATURE, 2003, 425 (6957) :475-479
[9]   Caenorhabditis elegans ortholog of a diabetes susceptibility locus:: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer [J].
Forsythe, Michele E. ;
Love, Dona C. ;
Lazarus, Brooke D. ;
Kim, Eun Ju ;
Prinz, William A. ;
Ashwell, Gilbert ;
Krause, Michael W. ;
Hanover, John A. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (32) :11952-11957
[10]   Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change [J].
Gallagher, E ;
Gao, M ;
Liu, YC ;
Karin, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (06) :1717-1722