The Zebrafish Information Network: the zebrafish model organism database provides expanded support for genotypes and phenotypes

被引：120

作者：

Sprague, Judy ^{[1
]}

Bayraktaroglu, Leyla ^{[1
]}

Bradford, Yvonne ^{[1
]}

Conlin, Tom ^{[1
]}

Dunn, Nathan ^{[1
]}

Fashena, David ^{[1
]}

Frazer, Ken ^{[1
]}

Haendel, Melissa ^{[1
]}

Howe, Douglas G. ^{[1
]}

Knight, Jonathan ^{[1
]}

Mani, Prita ^{[1
]}

Moxon, Sierra A. T. ^{[1
]}

Pich, Christian ^{[1
]}

Ramachandran, Sridhar ^{[1
]}

Schaper, Kevin ^{[1
]}

Segerdell, Erik ^{[1
]}

Shao, Xiang ^{[1
]}

Singer, Amy ^{[1
]}

Song, Peiran ^{[1
]}

Sprunger, Brock ^{[1
]}

Van Slyke, Ceri E. ^{[1
]}

Westerfield, Monte ^{[1
]}

机构：

[1] Univ Oregon 5291, Zebrafish Informat Networ, Eugene, OR 97403 USA

来源：

NUCLEIC ACIDS RESEARCH | 2008年 / 36卷

关键词：

D O I：

10.1093/nar/gkm956

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Zebrafish Information Network (ZFIN, http://zfin.org), the model organism database for zebrafish, provides the central location for curated zebrafish genetic, genomic and developmental data. Extensive data integration of mutant phenotypes, genes, expression patterns, sequences, genetic markers, morpholinos, map positions, publications and community resources facilitates the use of the zebrafish as a model for studying gene function, development, behavior and disease. Access to ZFIN data is provided via web-based query forms and through bulk data files. ZFIN is the definitive source for zebrafish gene and allele nomenclature, the zebrafish anatomical ontology (AO) and for zebrafish gene ontology (GO) annotations. ZFIN plays an active role in the development of cross-species ontologies such as the phenotypic quality ontology (PATO) and the gene ontology (GO). Recent enhancements to ZFIN include (i) a new home page and navigation bar, (ii) expanded support for genotypes and phenotypes, (iii) comprehensive phenotype annotations based on anatomical, phenotypic quality and gene ontologies, (iv) a BLAST server tightly integrated with the ZFIN database via ZFIN-specific datasets, (v) a global site search and (vi) help with hands-on resources.

引用

页码：D768 / D772

页数：5

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