Comment on the cylindrical capacitor electrospray interface

被引：29

作者：

König, S

Fales, HM

机构：

[1] NHLBI, Biophys Chem Lab, NIH, Bethesda, MD 20892 USA

[2] Hoechst Marion Roussell, Res Ctr, Bridgewater, NJ 08807 USA

来源：

ANALYTICAL CHEMISTRY | 1998年 / 70卷 / 20期

关键词：

D O I：

10.1021/ac980169j

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Wang and Hackett have recently proposed (Anal. Chem. 1998, 70, 205-212) a new electrospray interface described as a "concentric cylindrical capacitor". Excellent spectra were obtained, especially in the negative ion mode, with lipid A, a 15-mer oligonucleotide, and a series of proteins. We find that similar results can be obtained merely by ensuring a direct electrical contact between the analyte inside a fused-silica capillary and the high-voltage supply. No capacitor effect need be invoked.

引用

页码：4453 / 4455

页数：3

共 10 条

[1]

ANDRIEN BA, 1997, P 54 ASMS C MASS SPE, P457

[2] MICRO-ELECTROSPRAY MASS-SPECTROMETRY - ULTRA-HIGH-SENSITIVITY ANALYSIS OF PEPTIDES AND PROTEINS [J].