Essential Elements of Genetic Cancer Risk Assessment, Counseling, and Testing: Updated Recommendations of the National Society of Genetic Counselors

被引：237

作者：

Riley, Bronson D. ^{[1
]}

Culver, Julie O. ^{[2
]}

Skrzynia, Cecile ^{[3
,4
]}

Senter, Leigha A. ^{[5
]}

Peters, June A. ^{[6
]}

Costalas, Josephine W. ^{[7
]}

Callif-Daley, Faith ^{[8
]}

Grumet, Sherry C. ^{[9
]}

Hunt, Katherine S. ^{[10
]}

Nagy, Rebecca S. ^{[11
,12
]}

McKinnon, Wendy C. ^{[13
]}

Petrucelli, Nancie M. ^{[14
]}

Bennett, Robin L. ^{[15
]}

Trepanier, Angela M. ^{[16
]}

机构：

[1] SE Nebraska Canc Ctr, Lincoln, NE USA

[2] City Hope Natl Med Ctr, Div Clin Canc Genet, Duarte, CA USA

[3] Univ N Carolina, Dept Med, Chapel Hill, NC USA

[4] Univ N Carolina, Dept Genet, Chapel Hill, NC USA

[5] Ohio State Univ, Div Human Genet, Columbus, OH 43210 USA

[6] NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, Rockville, MD USA

[7] St Mary Reg Canc Ctr, Langhorne, PA USA

[8] Childrens Med Ctr Dayton, Dept Med Genet, Dayton, OH USA

[9] Monmouth Med Ctr, Leon Hess Canc Ctr, Long Branch, NJ USA

[10] Mayo Coll Med, Scottsdale, AZ USA

[11] Ohio State Univ, Clin Canc Genet Program, James Canc Hosp, Columbus, OH 43210 USA

[12] Ohio State Univ, Solove Res Inst, Columbus, OH 43210 USA

[13] Fletcher Allen Hlth Care, Vermont Reg Genet Ctr, Dept Pediat, Burlington, VT USA

[14] Karmanos Canc Inst, Detroit, MI USA

[15] Univ Washington, Div Med Genet, Med Ctr, Seattle, WA 98195 USA

[16] Wayne State Univ, Sch Med, Ctr Mol Med & Genet, Detroit, MI USA

来源：

JOURNAL OF GENETIC COUNSELING | 2012年 / 21卷 / 02期

关键词：

Cancer genetic counseling; Risk assessment; Genetic testing; Family history; Psychosocial assessment; Hereditary cancer; Informed consent; BREAST-CANCER; LYNCH-SYNDROME; HEREDITARY CANCER; FAMILY-HISTORY; PSYCHOLOGICAL IMPACT; BRCA1; SUSCEPTIBILITY; PREDISPOSITION; WOMEN; COMMUNICATION;

D O I：

10.1007/s10897-011-9462-x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Updated from their original publication in 2004, these cancer genetic counseling recommendations describe the medical, psychosocial, and ethical ramifications of counseling at-risk individuals through genetic cancer risk assessment with or without genetic testing. They were developed by members of the Practice Issues Subcommittee of the National Society of Genetic Counselors Familial Cancer Risk Counseling Special Interest Group. The information contained in this document is derived from extensive review of the current literature on cancer genetic risk assessment and counseling as well as the personal expertise of genetic counselors specializing in cancer genetics. The recommendations are intended to provide information about the process of genetic counseling and risk assessment for hereditary cancer disorders rather than specific information about individual syndromes. Essential components include the intake, cancer risk assessment, genetic testing for an inherited cancer syndrome, informed consent, disclosure of genetic test results, and psychosocial assessment. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. These recommendations do not displace a health care provider's professional judgment based on the clinical circumstances of a client.

引用

页码：151 / 161

页数：11

共 79 条

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