TOPOGRAPHICAL DISTRIBUTION OF MOTOR FASCICLES IN THE SCIATIC-TIBIAL NERVE OF THE RAT

被引:72
作者
Badia, Jordi [1 ]
Pascual-Font, Aran [1 ]
Vivo, Meritxell [1 ]
Udina, Esther [1 ]
Navarro, Xavier [1 ]
机构
[1] Univ Autonoma Barcelona, Dept Cell Biol Physiol & Immunol, Inst Neurosci, Neuroplast & Regenerat Grp, E-08193 Barcelona, Spain
关键词
axonal tracing; motor fibers; peripheral nerve somatotopy; sciatic nerve; tibial nerve; PERIPHERAL-NERVES; MEDIAN NERVE; SOMATOTOPIC ORGANIZATION; SELECTIVE STIMULATION; ULNAR NERVE; AXONS; ACTIVATION; FIBERS; MUSCLE; REPAIR;
D O I
10.1002/mus.21652
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Knowledge of the intraneural topography of peripheral nerves may help to improve nerve repair after injuries and the selectivity of neural interfaces. We studied the fascicular pattern of motor fibers of the rat sciatic-tibial nerve. We carried out an anatomical dissection of the muscular tributaries of the tibial nerve in the leg. Immunohistochemistry against choline acetyltransferase was used to identify motor axons. Retrograde tracing allowed localization of the muscular fascicles at proximal levels of the sciatic trunk. The distribution of motor fibers in transverse section of the tibial nerve is not homogeneous; two clusters were identified, each one containing fibers of functionally related muscles. Retrograde tracing allowed for the identification of motor fascicles, each one well localized along the sciatic nerve. In the rat there is a somatotopic organization of the sciatic nerve, with muscular fascicles maintaining the same relative position along the entire nerve. Muscle Nerve 42: 192-201, 2010
引用
收藏
页码:192 / 201
页数:10
相关论文
共 51 条
[31]  
PUTTI V, 1916, CLIN CHIR, V24, P1021
[32]   IDENTIFYING MOTOR AND SENSORY MYELINATED AXONS IN RABBIT PERIPHERAL-NERVES BY HISTOCHEMICAL STAINING FOR CARBONIC-ANHYDRASE AND CHOLINESTERASE ACTIVITIES [J].
RILEY, DA ;
SANGER, JR ;
MATLOUB, HS ;
YOUSIF, NJ ;
BAIN, JLW ;
MOORE, GH .
BRAIN RESEARCH, 1988, 453 (1-2) :79-88
[33]   Polyimide cuff electrodes for peripheral nerve stimulation [J].
Rodríguez, FJ ;
Ceballos, D ;
Schüttler, M ;
Valero, A ;
Valderrama, E ;
Stieglitz, T ;
Navarro, X .
JOURNAL OF NEUROSCIENCE METHODS, 2000, 98 (02) :105-118
[34]  
Rodriguez FJ, 2004, DRUG DISCOV TODAY DI, V1, P177, DOI [10.1016/j.ddmod.2004.09.008, DOI 10.1016/J.DDMOD.2004.09.008]
[35]   MULTIELECTRODE SPIRAL CUFF FOR ORDERED AND REVERSED ACTIVATION OF NERVE-FIBERS [J].
ROZMAN, J ;
SOVINEC, B ;
TRLEP, M ;
ZORKO, B .
JOURNAL OF BIOMEDICAL ENGINEERING, 1993, 15 (02) :113-120
[36]   PERIPHERAL PROJECTIONS OF FASCICLES IN THE HUMAN MEDIAN NERVE [J].
SCHADY, W ;
OCHOA, JL ;
TOREBJORK, HE ;
CHEN, LS .
BRAIN, 1983, 106 (SEP) :745-760
[37]   A model of selective activation of the femoral nerve with a flat interface nerve electrode for a lower extremity neuroprosthesis [J].
Schiefer, Matthew A. ;
Triolo, Ronald J. ;
Tyler, Dustin J. .
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 2008, 16 (02) :195-204
[38]   FIBER COMPOSITION OF THE RAT SCIATIC-NERVE [J].
SCHMALBRUCH, H .
ANATOMICAL RECORD, 1986, 215 (01) :71-81
[39]   OPTIMAL AND DATA-BASED HISTOGRAMS [J].
SCOTT, DW .
BIOMETRIKA, 1979, 66 (03) :605-610
[40]   Peripheral nerve fascicles: Anatomy and clinical relevance [J].
Stewart, JD .
MUSCLE & NERVE, 2003, 28 (05) :525-541