Foxn4 -: a new member of the forkhead gene family is expressed in the retina

被引：36

作者：

Gouge, A

Holt, J

Hardy, AP

Sowden, JC

Smith, HK

机构：

[1] UCL, Wolfson Inst Biomed Res, Dept Biol, London WC1E 6BT, England

[2] UCL, Galton Lab, Dept Biol, London NW1 2HE, England

[3] UCL, Inst Child Hlth, London WC1N 1EH, England

来源：

MECHANISMS OF DEVELOPMENT | 2001年 / 107卷 / 1-2期

关键词：

mouse; forkhead; Foxn4; retina; spinal cord; hindbrain; in situ hybridisation; proliferation; ocular retardation;

D O I：

10.1016/S0925-4773(01)00465-8

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We report the cloning and expression of a novel murine forkhead/winged helix family member - Foxn4 that is expressed during neural development in the retina, the ventral hindbrain and spinal cord and dorsal midbrain. Retinal Foxn4 expression is associated with the zone of proliferating progenitor cells. In the Mouse mutant ocular retardation (or(J)), Foxn4 expression in the retina is significantly reduced and terminates prematurely. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：203 / 206

页数：4

共 16 条

[1] Ocular retardation mouse caused by Chx10 homeobox null allele: Impaired retinal progenitor proliferation and bipolar cell differentiation
Burmeister, M
Novak, T
Liang, MY
Basu, S
Ploder, L
Hawes, NL
Vidgen, D
Hoover, F
Goldman, D
Kalnins, VI
Roderick, TH
Taylor, BA
Hankin, MH
McInnes, RR
[J]. NATURE GENETICS, 1996, 12 (04) : 376 - 384
[2] The nuclear receptor transcription factor, retinoid-related orphan receptor β, regulates retinal progenitor proliferation
Chow, L
Levine, EM
Reh, TA
[J]. MECHANISMS OF DEVELOPMENT, 1998, 77 (02) : 149 - 164
[3] FOX M, 2000, PRACT APPROACH SER, V217, P154
[4] EARLY GANGLION-CELL DIFFERENTIATION IN MOUSE RETINA - ELECTRON-MICROSCOPIC ANALYSIS UTILIZING SERIAL SECTIONS
HINDS, JW
HINDS, PL
[J]. DEVELOPMENTAL BIOLOGY, 1974, 37 (02) : 381 - 416
[5] CHROMOSOMAL LOCALIZATION OF THE GENE FOR AA-TYPE PLATELET-DERIVED GROWTH-FACTOR RECEPTOR (PDGFRA) IN HUMANS AND MICE
HSIEH, CL
NAVANKASATTUSAS, S
ESCOBEDO, JA
WILLIAMS, LT
FRANCKE, U
[J]. CYTOGENETICS AND CELL GENETICS, 1991, 56 (3-4): : 160 - 163
[6] Jensen AM, 1997, DEVELOPMENT, V124, P363
[7] Kaestner KH, 2000, GENE DEV, V14, P142
[8] Five years on the wings of fork head
Kaufmann, E
Knochel, W
[J]. MECHANISMS OF DEVELOPMENT, 1996, 57 (01) : 3 - 20
[9] HEPATOCYTE NUCLEAR FACTOR 3/FORK HEAD OR WINGED HELIX PROTEINS - A FAMILY OF TRANSCRIPTION FACTORS OF DIVERSE BIOLOGIC FUNCTION
LAI, E
CLARK, KL
BURLEY, SK
DARNELL, JE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (22) : 10421 - 10423
[10] Characterization of the human TBX20 gene, a new member of the T-box gene family closely related to the Drosophila H15 gene
Meins, M
Henderson, DJ
Bhattacharya, SS
Sowden, JC
[J]. GENOMICS, 2000, 67 (03) : 317 - 332

← 1 2 →