Nonpolarized memory T cells

被引：24

作者：

Kim, CH ^{[1
]}

Campbell, DJ

Butcher, EC

机构：

[1] Stanford Univ, Dept Pathol, Lab Immunol & Vasc Biol, Stanford, CA 94305 USA

[2] Vet Affairs Palo Alto Hlth Care Syst, Ctr Mol Biol & Med, Palo Alto, CA 94304 USA

来源：

TRENDS IN IMMUNOLOGY | 2001年 / 22卷 / 10期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S1471-4906(01)02029-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Nonpolarized T cells, defined as memory T cells that are deficient in the production of T helper 1 (Th1) or Th2 cytokines, are now receiving overdue attention. Predominantly of a lymphoid-tissue-homing phenotype, they comprise a memory T-cell pool for efficient secondary immune responses, as well as a CXC-chemokine receptor 5 (CXCR5)(+) T-cell subset specialized to provide help for B cells. Thus, the conventionally overlooked, nonpolarized T-cell population is proving to have diverse activities important to immune function.

引用

页码：527 / 530

页数：4