Artificial cells: building bioinspired systems using small-scale biology

被引：77

作者：

Zhang, Ying ^{[1
]}

Ruder, Warren C. ^{[2
]}

LeDuc, Philip R. ^{[1
,2
,3
]}

机构：

[1] Carnegie Mellon Univ, Dept Mech Engn, Pittsburgh, PA 15213 USA

[2] Carnegie Mellon Univ, Dept Biomed Engn, Pittsburgh, PA 15213 USA

[3] Carnegie Mellon Univ, Dept Biol Sci, Pittsburgh, PA 15213 USA

来源：

TRENDS IN BIOTECHNOLOGY | 2008年 / 26卷 / 01期

关键词：

D O I：

10.1016/j.tibtech.2007.09.006

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Artificial cells have generated much interest since the concept was introduced by Aleksandr Oparin in the 1920s, and they have had an impact on the pharmaceutical and biotechnology industry in various areas, including potential therapeutic applications. Here, we discuss the development of small-scale, bio-inspired artificial cell components that recreate the function of key cellular and physiological systems. We describe artificial cells, selected current applications and how small-scale biology could be used to provide what might be a next-generation approach in this area. We believe that this type of work is in its infancy and that exploiting small-scale biological inspiration in the field of artificial cells has great potential for successes in the future.

引用

页码：14 / 20

页数：7

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