Non-synaptic neuronal mechanisms of learning and memory in gastropod molluscs

被引：23

作者：

Benjamin, Paul R. ^{[1
]}

Kemenes, Gyoergy ^{[1
]}

Kemenes, Ildiko ^{[1
]}

机构：

[1] Univ Sussex, Sussex Ctr Neurosci, Sch Life Sci, Brighton BN7 2BB, E Sussex, England

来源：

FRONTIERS IN BIOSCIENCE | 2008年 / 13卷

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

learning and memory; non-synaptic; electrical excitability; classical conditioning; membrane potential; input resistance; plateauing; molluscs; review;

D O I：

10.2741/2993

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Gastropod molluscs provide important model systems for investigating the behavioral and neural basis of associative and non-associative learning. Habituation, sensitization, classical and operant conditioning are studied in motor reflex and central pattern generator circuits. Although synaptic plasticity has long been recognized as playing a key role in molluscan learning circuits, non-synaptic changes resulting in alterations in the excitability of neurons are increasingly recognized as an essential component of the memory trace.

引用

页码：4051 / 4057

页数：7

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