The crystal structure of a cyclic glycolipid reveals a carbohydrate-carbohydrate interaction interface

被引：12

作者：

Murphy, PV ^{[1
]}

Müller-Bunz, H ^{[1
]}

Velasco-Torrijos, T ^{[1
]}

机构：

[1] Univ Coll Dublin, Ctr Synth & Chem Biol, Dept Chem, Conway Inst Biomol & Biomed Res, Dublin 4, Ireland

来源：

CARBOHYDRATE RESEARCH | 2005年 / 340卷 / 07期

关键词：

crystal structure; glycolipid; macrocycle; hydrogen bonding; hydrophobic interaction;

D O I：

10.1016/j.carres.2005.02.026

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The crystal structure of an amphiphilic macrocycle [Velasco-Torrijos, T.; Murphy, P. V., Tetrahedron: Asymmetry 2005, 16, 261-272] derived from saccharides shows extensive hydrogen-bonding networks, including participation of water, that may have relevance for the modelling of carbohydrate-carbohydrate recognition at cell-cell interfaces. The structure may provide a basis for understanding the binding of the macrocycle to hydrophobic probes. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1437 / 1440

页数：4

共 11 条

[1] Carbohydrate-carbohydrate interaction as a major force initiating cell-cell recognition [J].