Riboflavin: The Health Benefits of a Forgotten Natural Vitamin

被引:336
作者
Suwannasom, Nittiya [1 ,2 ]
Kao, Ijad [1 ]
Pruss, Axel [1 ]
Georgieva, Radostina [1 ,3 ]
Baeumler, Hans [1 ]
机构
[1] Charite Univ Med Berlin, Ctr Tumor Med, Inst Transfus Med, Charitepl 1, D-10117 Berlin, Germany
[2] Univ Phayao, Sch Med Sci, Phayao 56000, Thailand
[3] Trakia Univ, Fac Med, Dept Med Phys, Biophys & Radiol, Stara Zagora 6000, Bulgaria
基金
欧盟地平线“2020”;
关键词
riboflavin; vitamin B2; complementary medicine; functional food; oxidative stress; cancer; neurodegeneration; muscular degeneration; HIGHLY PURIFIED VITAMIN-B-2; STAPHYLOCOCCUS-AUREUS INFECTION; ZYMOSAN-INDUCED PERITONITIS; LACTIC-ACID BACTERIA; DIETARY B VITAMIN; PATHOGEN INACTIVATION; OXIDATIVE STRESS; INDUCED SHOCK; ORAL DELIVERY; REDUCES EDEMA;
D O I
10.3390/ijms21030950
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
Riboflavin (RF) is a water-soluble member of the B-vitamin family. Sufficient dietary and supplemental RF intake appears to have a protective effect on various medical conditions such as sepsis, ischemia etc., while it also contributes to the reduction in the risk of some forms of cancer in humans. These biological effects of RF have been widely studied for their anti-oxidant, anti-aging, anti-inflammatory, anti-nociceptive and anti-cancer properties. Moreover, the combination of RF and other compounds or drugs can have a wide variety of effects and protective properties, and diminish the toxic effect of drugs in several treatments. Research has been done in order to review the latest findings about the link between RF and different clinical aberrations. Since further studies have been published in this field, it is appropriate to consider a re-evaluation of the importance of RF in terms of its beneficial properties.
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页数:22
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