Metallation of pyridin-2-yldiazines.: Use of pyridine ring as ortho-directing group.: Diazines.: Part 45

被引：13

作者：

Berghian, C

Darabantu, M

Turck, A

Plé, N

机构：

[1] Univ Rouen, IRCOF, F-76131 Mont St Aignan, France

[2] Univ Babes Bolyai, Dept Organ Chem, RO-400028 Cluj Napoca, Romania

来源：

TETRAHEDRON | 2005年 / 61卷 / 40期

关键词：

pyridin-2-yldiazines; metallation; functionalization; ortho-directing group;

D O I：

10.1016/j.tet.2005.07.031

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from commercial chlorodiazines, we report the synthesis of pyridin-2-yidiazines. The first lithiation and functionalization of these compounds are reported and the regioselectivity of the metallation is discussed. The functionalization via the metallation reaction, provides a new access to substituted pyridin-2-yldiazines, which could be used as building blocks in supramolecules. (c) 2005 Elsevier Ltd. All rights reserved.

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收藏

页码：9637 / 9644

页数：8

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