Express protocol for functionalization of polymer supports for oligonucleotide synthesis

被引：22

作者：

Kumar, P

Sharma, AK

Sharma, P

Garg, BS

Gupta, KC

机构：

[1] CTR BIOCHEM TECHNOL,NUCLEIC ACIDS RES LAB,DELHI 110007,INDIA

[2] UNIV DELHI,DEPT CHEM,DELHI 110007,INDIA

来源：

NUCLEOSIDES & NUCLEOTIDES | 1996年 / 15卷 / 04期

关键词：

D O I：

10.1080/07328319608002134

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A rapid and general one-pot method is described for the attachment of the leader nucleoside onto the polymer supports, suitable for polymer supported oligonucleotide synthesis following oxidation- reduction condensation. The method can also be used for support functionalisation in fully automated DNA synthesizer prior to oligonucleotide synthesis.

引用

收藏

页码：879 / 888

页数：10

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