Merging Visible-Light Photocatalysis and Transition-Metal Catalysis in the Copper-Catalyzed Trifluoromethylation of Boronic Acids with CF3I

被引：608

作者：

Ye, Yingda ^{[1
]}

Sanford, Melanie S. ^{[1
]}

机构：

[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 22期

关键词：

RADICAL TRIFLUOROMETHYLATION; FLUORINE; CHEMISTRY; PALLADIUM; RHODIUM;

D O I：

10.1021/ja301553c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This communication describes the development of a mild method for the cross-coupling of arylboronic acids with CF3I via the merger of photoredox and Cu catalysis. This method has been applied to the trifluoromethylation of electronically diverse aromatic and heteroaromatic substrates and tolerates many common functional groups.

引用

页码：9034 / 9037

页数：4

共 54 条

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