2-substituted-3-allenyl-benzo[b]furans through the palladium-catalysed cyclization of propargylic o-(alkynyl)phenyl ethers.

被引:114
作者
Cacchi, S [1 ]
Fabrizi, G [1 ]
Moro, L [1 ]
机构
[1] Univ La Sapienza, Dipartimento Studi Chim & Tecnol Sostanze Biol At, I-00185 Rome, Italy
关键词
D O I
10.1016/S0040-4039(98)00936-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The reaction of propargylic o-(alkynyl)phenyl ethers in the presence of' Pd(PPh3)(4) and K2CO3 affords 2-substituted-3-allenylbenzo [b] furans in good yields. Depending on the nature of the starting alkyne, variable amounts of isomeric 2-substituted-3-propargylbenzo[b]furans have bren isolated. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:5101 / 5104
页数:4
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