A comparative study of adhesion formation and abdominal wall ingrowth after laparoscopic ventral hernia repair in a porcine model using multiple types of mesh

被引：56

作者：

McGinty, JJ ^{[1
]}

Hogle, NJ ^{[1
]}

McCarthy, H ^{[1
]}

Fowler, DL ^{[1
]}

机构：

[1] Cornell Univ, Weill Med Coll, New York, NY 10021 USA

来源：

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES | 2005年 / 19卷 / 06期

关键词：

laparoscopic; ventral hernia; incisional hernia; mesh; adhesions;

D O I：

10.1007/s00464-004-8174-9

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background: The ideal mesh for laparoscopic ventral hernia repair is not yet identified. Methods: We laparoscopically placed polypropylene (PPM), expanded polytetrafluoroethylene (ePTFE), and polyester with antiadhesive collagen layer (PCO) in eight pigs using sutures and tacks for fixation. After 28-day survival, we compared adhesion formation, fibrous ingrowth, and shrinkage among the types of mesh. Results: Mean area of adhesions to PCO (8.25 %) was less than that to ePTFE (57.14 %, p < 0.001) or PPM (79.38 %, p < 0.001). Adhesions peel strength was less for PCO (2.3 N) than for PPM (16.1 N, p < 0.001) or ePTFE (8.8 N, p = 0.02). Peel strength of mesh from the abdominal wall was less for ePTFE (1.3 N/cm of mesh width) than for PCO (2.8 N/cm, p = 0.001) or PPM (2.1 N/cm, p = 0.05). ePTFE area (94.4 cm 2) was 2 less than that for PCO (118.6 cm, p < 0.001) or PPM (140.7 cm(2), P < 0.02). Conclusion: PCO had fewer and less severe adhesions than ePTFE or PPM while facilitating excellent ingrowth of the adjacent parietal tissue.

引用

页码：786 / 790

页数：5

共 18 条

[1] EXPERIMENTAL EVALUATION OF A NEW COMPOSITE MESH WITH THE SELECTIVE PROPERTY OF INCORPORATION TO THE ABDOMINAL-WALL WITHOUT ADHERING TO THE INTESTINES [J].