Nanoscale microcavity sensor for single particle detection

被引:124
作者
Lee, Mindy R. [1 ]
Fauchet, Philippe M. [1 ,2 ]
机构
[1] Univ Rochester, Inst Opt, Rochester, NY 14627 USA
[2] Univ Rochester, Dept Elect & Comp Engn, Rochester, NY 14627 USA
关键词
D O I
10.1364/OL.32.003284
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Recently we demonstrated a biosensor based on a two-dimensional photonic crystal microcavity for detection of proteins. We present a theoretical and experimental study of a modified structure for single particle detection. With an active sensing volume of similar to 0.15 mu m(3), the device is capable of detecting similar to 1 fg of matter. Its performance is tested with latex spheres with sizes that fall in the size range of a variety of viruses. (c) 2007 Optical Society of America.
引用
收藏
页码:3284 / 3286
页数:3
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