Synthesis of new chiral catalysts, pyridyl- and bipyridylalcohols, for the enantioselective addition of diethylzinc to benzaldehyde

被引：43

作者：

Collomb, P

von Zelewsky, A

机构：

[1] Novartis Nutr Res, CH-3176 Neuenegg, Switzerland

[2] Univ Fribourg, Inst Inorgan & Analyt Chem, CH-1700 Fribourg, Switzerland

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 21期

关键词：

D O I：

10.1016/S0957-4166(98)00399-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

New chiral ligands, pyridyl- and bipyridylalcohols, were prepared and their catalytic role in the reaction of diethylzinc with benzaldehyde to give 1-phenyl-1-propanol was studied. In several cases, the yields approach 100%, and ee-values of up to 86% are observed. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：3911 / 3917

页数：7

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