2,2-Dimethyl-2H-anthra[2,3-b]pyran-6,11-diones:: A new class of cytotoxic compounds

被引：17

作者：

Melliou, E ^{[1
]}

Magiatis, P

Mitaku, S

Skaltsounis, AL

Pierré, A

Atassi, G

Renard, P

机构：

[1] Univ Athens, Lab Pharmacognosy, GR-15771 Athens, Greece

[2] Inst Rech SERVIER, F-92150 Suresnes, France

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 2001年 / 9卷 / 03期

关键词：

D O I：

10.1016/S0968-0896(00)00278-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis and cytotoxic activity of some new 2,2-dimethyl-2H anthra[2,3-b]pyran-6,11-diones is described. Certain compounds possess interesting activity against murine leukemia L-1210 cells. Relationships between the biological activity and the pyrano-ring conformations are discussed. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：607 / 612

页数：6

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