Sensorimotor attenuation by central motor command signals in the absence of movement

被引:156
作者
Voss, M
Ingram, JN
Haggard, P
Wolpert, DM
机构
[1] Inst Neurol, Sobell Dept Motor Neurosci, London WC1N 3BG, England
[2] Inst Cognit Neurosci, London WC1N 3AR, England
[3] Dept Psychol, London WC1N 3AR, England
基金
英国惠康基金;
关键词
D O I
10.1038/nn1592
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Voluntary actions typically produce suppression of afferent sensation from the moving body part. We used transcranial magnetic stimulation to delay the output of motor commands from the motor cortex during voluntary movement. We show attenuation of sensation during this delay, in the absence of movement. We conclude that sensory suppression mainly relies on central signals related to the preparation for movement and that these signals are upstream of primary motor cortex.
引用
收藏
页码:26 / 27
页数:2
相关论文
共 15 条
[1]   Spatio-temporal prediction modulates the perception of self-produced stimuli [J].
Blakemore, SJ ;
Frith, CD ;
Wolpert, DM .
JOURNAL OF COGNITIVE NEUROSCIENCE, 1999, 11 (05) :551-559
[2]  
CHAPMAN CE, 1987, EXP BRAIN RES, V68, P516
[3]   LOCALIZATION, TIMING AND SPECIFICITY OF GATING OF SOMATOSENSORY EVOKED-POTENTIALS DURING ACTIVE MOVEMENT IN MAN [J].
COHEN, LG ;
STARR, A .
BRAIN, 1987, 110 :451-467
[4]   DELAY IN THE EXECUTION OF VOLUNTARY MOVEMENT BY ELECTRICAL OR MAGNETIC BRAIN-STIMULATION IN INTACT MAN - EVIDENCE FOR THE STORAGE OF MOTOR PROGRAMS IN THE BRAIN [J].
DAY, BL ;
ROTHWELL, JC ;
THOMPSON, PD ;
DENOORDHOUT, AM ;
NAKASHIMA, K ;
SHANNON, K ;
MARSDEN, CD .
BRAIN, 1989, 112 :649-663
[5]   Supplementary motor area provides an efferent signal for sensory suppression [J].
Haggard, P ;
Whitford, B .
COGNITIVE BRAIN RESEARCH, 2004, 19 (01) :52-58
[6]   THE PROCESSING OF HUMAN BALLISTIC MOVEMENTS EXPLORED BY STIMULATION OVER THE CORTEX [J].
PALMER, E ;
CAFARELLI, E ;
ASHBY, P .
JOURNAL OF PHYSIOLOGY-LONDON, 1994, 481 (02) :509-520
[7]   DIFFERENTIATION OF SENSORIMOTOR NEURONAL STRUCTURES RESPONSIBLE FOR INDUCTION OF MOTOR EVOKED-POTENTIALS, ATTENUATION IN DETECTION OF SOMATOSENSORY STIMULI, AND INDUCTION OF SENSATION OF MOVEMENT BY MAPPING OF OPTIMAL CURRENT DIRECTIONS [J].
PASCUALLEONE, A ;
COHEN, LG ;
BRASILNETO, JP ;
VALLSSOLE, J ;
HALLETT, M .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1994, 93 (03) :230-236
[8]   Sensory input to primate spinal cord is presynaptically inhibited during voluntary movement [J].
Seki, K ;
Perlmutter, SI ;
Fetz, EE .
NATURE NEUROSCIENCE, 2003, 6 (12) :1309-1316
[9]   SUPPRESSION OF CUTANEOUS PERCEPTION BY MAGNETIC PULSE STIMULATION OF THE HUMAN BRAIN [J].
SEYAL, M ;
MASUOKA, LK ;
BROWNE, JK .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1992, 85 (06) :397-401
[10]   Two eyes for an eye: The neuroscience of force escalation [J].
Shergill, SS ;
Bays, PM ;
Frith, CD ;
Wolpert, DM .
SCIENCE, 2003, 301 (5630) :187-187