Motor-cognitive approach and aerobic training: a synergism for rehabilitative intervention in Parkinson's disease

被引:38
作者
Ferrazzoli, Davide [1 ]
Ortelli, Paola [1 ]
Cucca, Alberto [2 ,3 ]
Bakdounes, Leila [2 ]
Canesi, Margherita [1 ]
Volpe, Daniele [2 ]
机构
[1] Moriggia Pelascini Hosp Gravedona & Uniti, Fresco Parkinson Ctr, Dept Parkinsons Dis Movement Disorders & Brain In, I-22015 Como, Italy
[2] Fresco Parkinson Ctr, S Stefano Riabilitazione, I-36057 Vicenza, Italy
[3] NYU, Sch Med, Dept Neurol, Marlene & Paolo Fresco Inst Parkinsons & Movement, New York, NY 10017 USA
关键词
aerobic exercise; motor-cognitive rehabilitation; neuroplasticity; Parkinson's disease; quality of life; QUALITY-OF-LIFE; DIRECT-CURRENT STIMULATION; BASAL GANGLIA FUNCTION; DOPAMINE D2 RECEPTOR; REDUCE FALL RISK; PHYSICAL-THERAPY; NEUROTROPHIC FACTOR; VIRTUAL-REALITY; TREADMILL EXERCISE; OLDER-ADULTS;
D O I
10.2217/nmt-2019-0025
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Parkinson's disease (PD) results in a complex deterioration of motor behavior. Effective pharmacological or surgical treatments addressing the whole spectrum of both motor and cognitive symptoms are lacking. The cumulative functional impairment may have devastating socio-economic consequences on both patients and caregivers. Comprehensive models of care based on multidisciplinary approaches may succeed in better addressing the overall complexity of PD. Neurorehabilitation is a highly promising non-pharmacological intervention for managing PD. The scientific rationale beyond rehabilitation and its practical applicability remain to be established. In the present perspective, we aim to discuss the current evidence supporting integrated motor-cognitive and aerobic rehabilitation approaches for patients with PD while suggesting a practical framework to optimize this intervention in the next future.
引用
收藏
页码:41 / 55
页数:15
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