Cadherins constitute a superfamily of cell adhesion molecules involved in cell-cell interaction, histogenesis and cellular transformation. They have been implicated in the development of various lineages, including derivatives of the neural crest. Neural crest cells (NCC) emerge from the dorsal part of the neural tube after an epithelio-mesenchymal transition (EMT) and migrate through the embryo. After homing and differentiation, NCC give rise to many cell types, such as neurons, Schwann cells and melanocytes. During these steps, the pattern of expression of the various cadherins studied is very dynamic. Cadherins also display plasticity of expression during the transformation of neural crest cell derivatives. Here, we review the pattern of expression and the role of the main cadherins involved in the development and transformation of neural crest cell derivatives. (C) 2001 Wiley-Liss, Inc.
机构:
Washington Univ, Sch Med, Dept Ophthalmol & Visual Sci, Cataract Res Ctr, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Ophthalmol & Visual Sci, Cataract Res Ctr, St Louis, MO 63110 USA
Beebe, DC
Coats, JM
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机构:Washington Univ, Sch Med, Dept Ophthalmol & Visual Sci, Cataract Res Ctr, St Louis, MO 63110 USA
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FAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCEFAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCE
BOULAY, JL
DENNEFELD, C
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FAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCEFAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCE
DENNEFELD, C
ALBERGA, A
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FAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCEFAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCE
机构:
Washington Univ, Sch Med, Dept Ophthalmol & Visual Sci, Cataract Res Ctr, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Ophthalmol & Visual Sci, Cataract Res Ctr, St Louis, MO 63110 USA
Beebe, DC
Coats, JM
论文数: 0引用数: 0
h-index: 0
机构:Washington Univ, Sch Med, Dept Ophthalmol & Visual Sci, Cataract Res Ctr, St Louis, MO 63110 USA
机构:
FAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCEFAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCE
BOULAY, JL
DENNEFELD, C
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h-index: 0
机构:
FAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCEFAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCE
DENNEFELD, C
ALBERGA, A
论文数: 0引用数: 0
h-index: 0
机构:
FAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCEFAC MED STRASBOURG,INSERM,U 184,CNRS,GENET MOLEC EUCARYOTES LAB,11 RUE HUMANN,F-67085 STRASBOURG,FRANCE