Highways of gene sharing in prokaryotes

被引:349
作者
Beiko, RG
Harlow, TJ
Ragan, MA [1 ]
机构
[1] Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia
[2] Univ Queensland, Australian Res Council, Ctr Bioinformat, Brisbane, Qld 4072, Australia
关键词
lateral genetic transfer; microbial genomes; molecular phylogeny;
D O I
10.1073/pnas.0504068102
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The extent to which lateral genetic transfer has shaped microbial genomes has major implications for the emergence of community structures. We have performed a rigorous phylogenetic analysis of > 220,000 proteins from genomes of 144 prokaryotes to determine the contribution of gene sharing to current prokaryotic diversity, and to identify "highways" of sharing between lineages. The inferred relationships suggest a pattern of inheritance that is largely vertical, but with notable exceptions among closely related taxa, and among distantly related organisms that live in similar environments.
引用
收藏
页码:14332 / 14337
页数:6
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