Active trifluoromethylating agents from well-defined copper(I)-CF3 complexes

被引：347

作者：

Dubinina, Galyna G. ^{[1
]}

Furutachi, Hideki ^{[2
]}

Vicic, David A. ^{[1
]}

机构：

[1] Univ Hawaii, Dept Chem, Honolulu, HI 96822 USA

[2] Kanazawa Univ, Div Mat Sci, Grad Sch Nat Sci & Technol, Kanazawa, Ishikawa 9201192, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 27期

关键词：

D O I：

10.1021/ja802946s

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first examples of isolable and structurally characterized Cu(I)-CF3 complexes are reported. N-Heterocyclic carbene (NHC)-supported copper tert-butoxide complexes reacted with Me3Si-CF3 to afford new (NHC)Cu-CF3 complexes whose structures were dependent on whether or not the C-4-C-5 positions of the five-membered NHC rings were saturated. In situ generated (Sl/Pr)Cu-CF3 cleanly transferred its trifluoromethyl group to a number of organic halides under mild conditions.

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页码：8600 / +

页数：3

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