Dysregulation of matrix metalloproteinases and their tissue inhibitors by S100A4

被引：17

作者：

Elenjord, Renate ^{[1
]}

Ljones, Hilde ^{[1
]}

Sundkvist, Elisabeth ^{[1
]}

Loennechen, Thrina ^{[1
]}

Winberg, Jan Olof ^{[2
]}

机构：

[1] Univ Tromso, Dept Pharm, N-9037 Tromso, Norway

[2] Univ Tromso, Dept Med Biol, N-9037 Tromso, Norway

来源：

CONNECTIVE TISSUE RESEARCH | 2008年 / 49卷 / 3-4期

关键词：

S100A4; matrix metalloproteinases; tissue inhibitors of matrix metalloproteinases; matrix degradation; invasion; cellular motility;

D O I：

10.1080/03008200802143125

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The S100A4 protein as well as the matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are associated with diseases such as arthritis and cancer. This mini review focuses on in vitro and in vivo studies indicating S100A4 involvement in regulation of MMPs and TIMPs, and the biological and pathobiological consequences of this regulation.

引用

收藏

页码：185 / 188

页数：4

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