A simple route to a novel enantiomerically pure P-chiral phosphine ligand containing a tertiary amide functional group

被引：31

作者：

Leung, PH ^{[1
]}

Loh, SK ^{[1
]}

Mok, KF ^{[1
]}

White, AJP ^{[1
]}

Williams, DJ ^{[1
]}

机构：

[1] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED, DEPT CHEM, LONDON SW7 2AY, ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 05期

关键词：

D O I：

10.1039/cc9960000591

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new palladium(II) complex containing an amido-substituted P-chiral phosphine ligand is prepared efficiently by the asymmetric Diels-Alder reaction between N,N-dimethylacrylamide and 1-phenyl-3,4-dimethylphosphole; the chelating properties of the functionalised ligand and the absolute configurations of the four newly generated stereocentres are determined by single-crystal X-ray analysis, and the optically active phosphine ligand displaced from the palladium template with 1,2-bis(diphenylphosphino)ethane.

引用

页码：591 / 592

页数：2

共 19 条

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