Highly selective, naked-eye and fluorescent "off-on" probe for detection of histidine/histidine-rich proteins and its application in living cell imaging

被引：21

作者：

Zhang, Shenyi ^{[1
]}

Yang, Chunmei ^{[1
]}

Zhu, Weiping ^{[1
]}

Zeng, Bubing ^{[1
]}

Yang, Youjun ^{[1
]}

Xu, Yufang ^{[1
]}

Qian, Xuhong ^{[1
]}

机构：

[1] E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 08期

基金：

国家高技术研究发展计划(863计划); 中国国家自然科学基金;

关键词：

AMINO-ACIDS; HISTIDINE; SENSOR; CHEMOSENSOR; PLASMA; ENSEMBLE; COMPLEX; SILVER;

D O I：

10.1039/c2ob06520g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly selective colorimetric and fluorescence enhanced probe S1 (M2@Cu) for histidine and histidine-rich proteins has been developed. In neutral aqueous ethanol solution, probe S1 can selectively detect histidine out of twenty DNA encoded amino acids by showing a color change from brownish red to light green, and with a fluorescence enhancement up to 99-fold at 537 nm, simultaneously.

引用

页码：1653 / 1658

页数：6

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