Virus-host interactions: new insights from the small RNA

被引:11
作者
Browne, EP
Li, JJ
Chong, M
Littman, DR [1 ]
机构
[1] NYU, Sch Med, Mol Pathogenesis Program, New York, NY 10016 USA
[2] NYU, Skirball Inst Biomol Med, Howard Hughes Med Inst, New York, NY 10016 USA
关键词
D O I
10.1186/gb-2005-6-11-238
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
RNA silencing has a known role in the antiviral responses of plants and insects. Recent evidence, including the finding that the Tat protein of human immunodeficiency virus (HIV) can suppress the host's RNA-silencing pathway and may thus counteract host antiviral RNAs, suggests that RNA-silencing pathways could also have key roles in mammalian virus-host interactions.
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页数:4
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共 24 条
[1]   Toll-like receptor signalling [J].
Akira, S ;
Takeda, K .
NATURE REVIEWS IMMUNOLOGY, 2004, 4 (07) :499-511
[2]   The functions of animal microRNAs [J].
Ambros, V .
NATURE, 2004, 431 (7006) :350-355
[3]   MicroRNAs: Genomics, biogenesis, mechanism, and function (Reprinted from Cell, vol 116, pg 281-297, 2004) [J].
Bartel, David P. .
CELL, 2007, 131 (04) :11-29
[4]   RNA silencing in plants [J].
Baulcombe, D .
NATURE, 2004, 431 (7006) :356-363
[5]   Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing [J].
Bennasser, Y ;
Le, SY ;
Benkirane, M ;
Jeang, KT .
IMMUNITY, 2005, 22 (05) :607-619
[6]   Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells [J].
Cai, XZ ;
Lu, SH ;
Zhang, ZH ;
Gonzalez, CM ;
Damania, B ;
Cullen, BR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (15) :5570-5575
[7]   TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing [J].
Chendrimada, TP ;
Gregory, RI ;
Kumaraswamy, E ;
Norman, J ;
Cooch, N ;
Nishikura, K ;
Shiekhattar, R .
NATURE, 2005, 436 (7051) :740-744
[8]  
Cullen BR, 2005, AIDS REV, V7, P22
[9]   Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding [J].
Garrus, JE ;
von Schwedler, UK ;
Pornillos, OW ;
Morham, SG ;
Zavitz, KH ;
Wang, HE ;
Wettstein, DA ;
Stray, KM ;
Côté, M ;
Rich, RL ;
Myszka, DG ;
Sundquist, WI .
CELL, 2001, 107 (01) :55-65
[10]   TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing [J].
Haase, AD ;
Jaskiewicz, L ;
Zhang, HD ;
Lainé, S ;
Sack, R ;
Gatignol, A ;
Filipowicz, W .
EMBO REPORTS, 2005, 6 (10) :961-967