Haptoglobin Genotype and Its Role in Diabetic Cardiovascular Disease

被引：50

作者：

Costacou, Tina ^{[1
]}

Levy, Andrew P. ^{[2
]}

机构：

[1] Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15213 USA

[2] Technion Israel Inst Technol, Technion Fac Med, Haifa, Israel

来源：

JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH | 2012年 / 5卷 / 04期

关键词：

Haptoglobin genotype; Cardiovascular disease; Diabetes; VITAMIN-E SUPPLEMENTATION; CORONARY-ARTERY CALCIFICATION; HEMOGLOBIN SCAVENGER RECEPTOR; MIDDLE-AGED INDIVIDUALS; LOW-DENSITY-LIPOPROTEIN; ACUTE-PHASE PROTEINS; BETA-CAROTENE; IN-VITRO; RISK-FACTOR; VASCULAR COMPLICATIONS;

D O I：

10.1007/s12265-012-9361-z

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Over the past decade, several longitudinal epidemiological studies have brought attention to the haptoglobin genotype and its importance in determining diabetic vascular disease risk. This manuscript presents an overview of the biology of the haptoglobin genotype and reviews the literature concerning its role in the development of cardiovascular disease among individuals with diabetes mellitus.

引用

页码：423 / 435

页数：13