Tunable, High Modulus Hydrogels Driven by Ionic Coacervation

被引：315

作者：

Hunt, Jasmine N.

Feldman, Kathleen E.

Lynd, Nathaniel A.

Deek, Joanna

Campos, Luis M.

Spruell, Jason M.

Hernandez, Blanca M.

Kramer, Edward J. ^{[1
]}

Hawker, Craig J.

机构：

[1] Univ Calif Santa Barbara, Dept Mat, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

ADVANCED MATERIALS | 2011年 / 23卷 / 20期

基金：

美国国家科学基金会;

关键词：

DOUBLE-NETWORK HYDROGELS; COMPLEX COACERVATION; DIBLOCK COPOLYMERS; BLOCK-COPOLYMERS; AQUEOUS-SOLUTION; MICELLES; DELIVERY; RAFT; INTERPOLYELECTROLYTE; CHEMISTRY;

D O I：

10.1002/adma.201004230

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A modular strategy for hydrogel formation based on the self-organization of well-defined ABA triblock copolyelectrolytes through ionic interactions in water is reported. The nature of the ionic domains, which constitute the physical crosslinks, provides for robust, yet highly tunable materials. These materials represent a diverse platform for hydrogel formation with enhanced mechanical properties and ease of synthesis while retaining a dynamic responsive nature.

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页码：2327 / +

页数：6

相关论文

共 39 条

[1] Poly(ethylene glycol) hydrogels formed by thiol-ene photopolymerization for enzyme-responsive protein delivery [J].

Aimetti, Alex A. ;

Machen, Alexandra J. ;

Anseth, Kristi S. .

BIOMATERIALS, 2009, 30 (30) :6048-6054

[2] Polyelectrolytes for cell encapsulation [J].

Bhatia, SR ;

Khattak, SF ;

Roberts, SC .

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, 2005, 10 (1-2) :45-51

[3] Phase Behavior and Coacervation of Aqueous Poly(acrylic acid)-Poly(allylamine) Solutions [J].

Chollakup, Rungsima ;

Smitthipong, Wirasak ;

Eisenbach, Claus D. ;

Tirrell, Matthew .

MACROMOLECULES, 2010, 43 (05) :2518-2528

[4] Hydrogel cell cultures [J].

Cushing, Melinda C. ;

Anseth, Kristi S. .

SCIENCE, 2007, 316 (5828) :1133-1134

[5] INFLUENCE OF PH ADJUSTMENT ON MICROCAPSULES OBTAINED FROM COMPLEX COACERVATION OF GELATIN AND ACACIA [J].

DANIELS, R ;

MITTERMAIER, EM .

JOURNAL OF MICROENCAPSULATION, 1995, 12 (06) :591-599

[6] Direct RAFT polymerization of an unprotected isocyanate-containing monomer and subsequent structopendant functionalization using "click"-type reactions [J].

Flores, Joel D. ;

Shin, Junghwan ;

Hoyle, Charles E. ;

McCormick, Charles L. .

POLYMER CHEMISTRY, 2010, 1 (02) :213-220

[7] Double-network hydrogels with extremely high mechanical strength [J].

Gong, JP ;

Katsuyama, Y ;

Kurokawa, T ;

Osada, Y .

ADVANCED MATERIALS, 2003, 15 (14) :1155-+

[8]

Gupta N, 2010, NAT CHEM, V2, P138, DOI [10.1038/NCHEM.478, 10.1038/nchem.478]

[9] Using polyelectrolyte block copolymers to tune nanostructure assembly [J].

Hales, Kelly ;

Pochan, Danin J. .

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, 2006, 11 (06) :330-336

[10] Thermoreversible ion gels with tunable melting temperatures from triblock and pentablock copolymers [J].

He, Yiyong ;

Lodge, Timothy P. .

MACROMOLECULES, 2008, 41 (01) :167-174

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