Assessing vascular permeability during experimental cerebral malaria by a radiolabeled monoclonal antibody technique

被引：37

作者：

van der Heyde, HC

Bauer, P

Sun, G

Chang, WL

Yin, LJ

Fuseler, J

Granger, DN

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Dept Microbiol & Immunol, Shreveport, LA 71130 USA

[2] Louisiana State Univ, Hlth Sci Ctr, Dept Cellular & Mol Physiol, Shreveport, LA 71130 USA

[3] Louisiana State Univ, Hlth Sci Ctr, Dept Med, Shreveport, LA 71130 USA

[4] Louisiana State Univ, Hlth Sci Ctr, Inflammat & Immunol Res Grp, Shreveport, LA 71130 USA

[5] Louisiana State Univ, Hlth Sci Ctr, Ctr Excellence Arthrit & Rheumatism, Shreveport, LA 71130 USA

来源：

INFECTION AND IMMUNITY | 2001年 / 69卷 / 05期

关键词：

D O I：

10.1128/IAI.69.5.3460-3465.2001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Vascular endothelial integrity, assessed by Evans blue dye extrusion and radiolabeled monoclonal antibody leakage, was markedly compromised in the brain, lung, kidney, and heart during Plasmodium berghei infection, a well-recognized model fur human cerebral malaria. The results for vascular permeability from both methods were significantly (P < 0.001) related.

引用

页码：3460 / 3465

页数：6

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