First total synthesis of fungerin an antifungal alkaloid from Fusarium sp.

被引:12
作者
Benhida, R [1 ]
Lezama, R [1 ]
Fourrey, JL [1 ]
机构
[1] CNRS, Inst Chim Subst Nat, F-91190 Gif Sur Yvette, France
关键词
D O I
10.1016/S0040-4039(98)01203-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The First total synthesis of fungerin 1, anew antifungal alkaloid, is described.Starting from a 4,5-diiodoimidazole derivative, the procedure involves regioselective prenylation and Heck type reaction steps to give 1 in high yield. (C) 1998 Elsevier Science Ltd. All rights reserved.
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页码:5963 / 5964
页数:2
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