Major bleeding complications in a specialized anticoagulation service

被引：58

作者：

Fanikos, J

Grasso-Correnti, N

Shah, R

Kucher, N

Goldhaber, SZ ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Med, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Pharm, Boston, MA 02115 USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2005年 / 96卷 / 04期

关键词：

D O I：

10.1016/j.amjcard.2005.03.104

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Major bleeding complications were investigated in 2,460 patients with 3,684 patient-years of warfarin exposure from 2000 to 2003. The most common indications for anticoagulation were atrial fibrillation (30%), venous thromboembolic disease (28%) and mechanical heart valve prosthesis (15%). Eleven patients had 12 nonfatal major bleeding complications, with no fatal bleeds during the study. The incidence of major bleeding complications was 0.12%/year; there were 0.32 bleeds/100 patient-years of coverage. Of the 12 bleeding events, 5 (42%) were intracranial hemorrhages. The average hospitalization cost per patient was $15,988, and the average length of hospitalization was 6.0 days. (c) 2005 Elsevier-Inc. All rights reserved.

引用

页码：595 / 598

页数：4

共 18 条

[11] The effect of excessive anticoagulation on mortality and morbidity in hospitalized patients with anticoagulant-related major hemorrhage [J].