Efficient oxidative conversion of aldehydes to 2-substituted oxazolines and oxazines using (diacetoxyiodo)benzene

被引：46

作者：

Karade, Nandkishor N. ^{[1
]}

Tiwari, Girdharilal B. ^{[1
]}

Gampawar, Sumit V. ^{[1
]}

机构：

[1] Swami Ramanand Teerth Marathwada Univ, Sch Chem Sci, Nanded 431606, Maharashtra, India

来源：

SYNLETT | 2007年 / 12期

关键词：

hypervalent iodine; oxazolines; oxazines; oxidation; aldehydes;

D O I：

10.1055/s-2007-982571

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of 2-substituted oxazolines from aldehydes and 2-amino alcohol using (diacetoxyiodo)benzene as an oxidant, is reported. (Diacetoxyiodo)benzene acts as a mild dehydrogenating agent to convert the initially formed oxazolidine from aldehyde and 2-amino alcohol to furnish 2-substituted oxazoline. Similarly, 3-aminopropanol and aldehydes gives the corresponding 2-substituted oxazines.

引用

页码：1921 / 1924

页数：4

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